Urinary bladder cancer treatment in India – choosing the right options

Imagine this. Everything is coming along fine in your life until you visit the washroom one day and suddenly discover that there is blood in urine. You feel no pain, no weakness, no fever. More likely than not, you ignore this – try to pass it off as a mild ‘infection’ and get on with your life. Until, after a few weeks, it happens again; And again. You visit your neighborhood physician who orders a few tests and an ultrasound exam. When the results come in you are shocked to discover that you have a mass in the urinary bladder, which is highly likely to be cancer.

Unfortunately, this is a common sequence of events for almost half a million people worldwide who are diagnosed to have urinary bladder cancer every year. The biggest impediment to effective and complete cure for bladder cancer is delay in diagnosis. The initial symptoms are all too often ignored by patients and doctors alike, while a curable cancer inexorably grows and spreads unnoticed to become life threatening. Bleeding in urine is a dangerous symptom and must not be ignored!

Smoking is the most common cause of urinary bladder cancer with about 50% of these tumors attributable to this single cause. Other causes – mostly unknown – account for the other half, and include exposure to certain chemicals and chronic infections of the bladder. Smoking is also a very important cause of recurrence of this disease in those who have already received treatment for urinary bladder cancer. Kicking the habit is essential to decrease the chances of bladder cancer coming back after initial treatment.

Urinary bladder cancer treatment in India is now quite standardized. Once a growth in the urinary bladder seen on ultrasound, the next step is to do a ‘cystoscopy’ which involves putting a thin telescope through the urinary passage into the urinary bladder under anesthesia. The tumor is visualized with a camera and is cut out and removed with specialized instruments. This procedure is called transurethral resection of bladder tumor (TURBT). This procedure not only removes the tumor but also provides vital information about the type (grade) and degree of spread (stage) of the cancer.

Depending upon the microscopic features of the tumor, bladder cancer can be either low grade (less aggressive) or high grade (more aggressive). This has important implications on further treatment. In terms of staging, it is vital to assess whether the bladder cancer is ‘superficial’, involving only the superficial (innermost) layers of the bladder or ‘muscle invasive’, which implies an infiltration of the cancer into the deep muscle layer of the urinary bladder.

For ‘superficial’ bladder cancer, the standard treatment involves regular follow up with repeated ‘cystoscopy’ examinations and the use of medications instilled directly into the bladder through the urinary passage at regular intervals. For ‘muscle invasive’ bladder tumors, the most effective treatment is to perform major surgery to remove the urinary bladder completely (radical cystectomy) and create a new bladder or tube using segments of intestine (urinary diversion, orthotopic neobladder or ileal conduit). While this has traditionally been performed via open surgery, urinary bladder cancer treatment in India is now getting revolutionized with the advent of robotic surgery.

Robotic surgery for bladder cancer offers a faster recovery, lesser blood loss, lesser pain and a possibility of a lower complication rate. Cancer control and cure rates are similar to open surgery.

In summary, smoking is the most common cause of urinary bladder cancer and blood in urine, its most common symptom. After initial removal via TURBT, subsequent treatment depends on the grade and stage of the disease. If required in a particular situation, robotic surgery for bladder cancer can improve outcomes and may be the next big revolution in urinary bladder cancer treatment in India.

This blog has been written by Dr. Gagan Gautam, Head of Urologic Oncology & Robotic surgery at Max Institute of Cancer Care, New Delhi, India. Dr. Gautam is a specialist doctor for prostate, kidney and urinary bladder cancer treatment in India and is the country’s leading expert in robotic surgery for these diseases. Max Institute of Cancer Care, a part of Max hospitals, Saket, New Delhi is a tertiary referral center regarded by many as the best hospital for bladder cancer treatment in India. It is equipped with state of the art facilities for radiation, chemotherapy and surgery for bladder cancer – including the Da Vinci Xi HD robotic surgical system. It is situated 20 minutes away from New Delhi’s international airport.

 To know more about, Dr. Gautam, please click here or visit his website www.roboticsurgerydelhi.com

 To connect with him on social media, please visit www.facebook.com/roboticsurgerydelhi or follow him on twitter @DrGaganGautam

 To seek an appointment or to get in touch with him, please click here

Robotic surgery is revolutionizing kidney cancer treatment in India

Hi tech robots performing complex operations on human beings through miniaturised instruments may sound like the stuff science fiction is made of …but it may be closer than you think. In fact, it is already here!

Robotic surgery has now entered the second decade since its inception around the turn of the century, and is now all set to revolutionise the way complex surgeries are performed. There are over 2000 surgical robots in the world today (>1500 in the US, ~ 20 in India) and they are increasingly being employed for the surgical treatment of cancers in India and abroad.

The most advanced robotic surgical system in the world today is the Da Vinci system developed by Intuitive Surgical (Sunnyvale, California, USA). It comprises of a console, patient side robotic machine and another cart, which houses the display monitor and lighting equipment. The surgeon sits at the console and through futuristic “master controls” initiates and controls the movements of robotic arms, which translate the movements of the surgeon to the robotic instruments inside the patient’s body. This system affords extremely precise and delicate movements made possible by the extreme miniaturization and flexibility of these special robotic instruments. Surgeon tremor is completely eliminated and the movements can be scaled (3:1) for greater finesse. Accompanying these advances in instrumentation, is the superb high definition magnified 3D vision of the operative field that the surgeon gets while sitting at the console of this robotic system. This enables the surgeon to see and appreciate minute structures inside the human body thereby making surgery potentially safer and more complete – aspects, which can be vital to a cancer patient.

Surgery for prostate cancer (robotic prostatectomy) is by far the most common cancer operation performed with robotic systems in the world today. Another condition in which the application of robotics is being considered a big step forward is – kidney cancer. Although relatively rare, kidney cancer is unique in being almost 100% curable if detected at an early stage when it is confined to the kidney and almost 100% fatal if it is detected at a stage when it has spread to other parts of the body. Kidney cancer treatment success rate is very high at early stage of the disease and very dismal at a late stage. Moreover, radiation and chemotherapy have been shown to be quite ineffective in this disease thereby leaving surgery as the only effective treatment option.

Surgery for kidney cancer broadly encompasses two separate types of operations – radical nephrectomy, in which the entire kidney is removed along with the tumor; and partial nephrectomy, which entails the selective removal of the cancerous portion of the kidney while sparing the rest of the kidney. Radical nephrectomy may be necessary in situations where the size of the tumor is large (typically more than 7 cm in greatest dimension) or when the location of the tumor makes it impossible to remove the tumor safely and completely without removing the entire kidney (as in the case of a tumor situated very close to the main blood vessels of the kidney). The removal of the entire kidney however, comes at a cost. The decrease in overall kidney function causes an adverse impact on the cardiovascular system and increases manifold, the chances of life-threatening complications later in life, such as heart attack and stroke. Moreover, in the long term, the chances of kidney failure and dependence on dialysis also increase significantly.

While radical nephrectomy may be inevitable in certain situations, most of the smaller and early stage tumors can be dealt with by the removal of the tumor itself while leaving the rest of the normal kidney behind (partial nephrectomy). In fact, it is universally acknowledged by all major cancer guidelines and medical associations that a partial nephrectomy achieves equal cancer cure for smaller tumors (<7 cm) as compared to a radical nephrectomy. At the same time, it enables the preservation of the maximum amount of normal kidney tissue and decreases the chances of heart attacks, strokes and dependence on dialysis. So overall, patients with small tumors in the kidney are likely to live longer, healthier lives if they choose to undergo partial nephrectomy rather than a complete removal of the kidney.

Though there are a number of ways of doing a partial nephrectomy (open, laparoscopic and robotic), robotic surgery has recently completely transformed the landscape in this type of kidney cancer treatment. In a number of major cancer centers in the western world, robotic surgery is now being used to perform over 90% of the total partial nephrectomy surgeries performed. Robotic surgery is also being increasingly used for kidney cancer treatment in India. The advantages of robotics in this operation are clear – excellent vision and dexterous fine instruments enable precise removal of the tumor and reconstruction of the remaining kidney with superior results and decreased complications. Since the operation is performed through small “keyhole” cuts without the need of a big open incision, the patient recovers faster, has less pain and is able to become fully active much earlier than conventional open kidney cancer surgery. Moreover, blood loss during the operation is significantly reduced and over 95% of patients do not require any blood transfusion thereby decreasing the transmission of blood borne infections.

The technology however doesn’t come cheap. The purchase and maintenance of the robot carries a cost, which invariably finds its way into the patients’ hospital bills. Using the robot inflates the cost of kidney cancer treatment in India by about 30% but some of this increased cost gets offset by the early discharge and less medications required after the operation. The chances of requiring readmission to the hospital also decreases, thereby decreasing the overall cost of kidney cancer treatment.

As the awareness regarding robotic surgery spreads in the country and as more and more robotic systems are installed in the top cancer hospitals in India, it is inevitable that an increasing number and types of procedures will be performed with the help of this technology. Already the robot is being used in a variety of different surgical specialties including gynecology, head and neck surgery and cardiac/thoracic surgery. This is only going to increase in the future. All this should translate into a significant improvement in the surgical care that is currently available at our medical institutions and enable surgeons to provide a relatively pain free, safe and effective solution for a gamut of diseases.

There is however, one important caveat that must be borne in mind prior to undergoing robotic surgery. Like any new technology, robotic surgery has a definite learning curve and requires specific training and experience in this modality. It may take up to 200 cases for a surgeon to become proficient in robotic surgery and become comfortable with this interface, which is completely different from open and conventional laparoscopic (“keyhole”) surgery. Although the technology is superlative, it is the man behind the machine that delivers the results.

This blog has been written by Dr. Gagan Gautam, head of urological cancer surgery and robotic surgery at Max Institute of Cancer Care, New Delhi, India. Dr. Gautam is the leading specialist for prostate, urinary bladder and kidney cancer treatment in India and is an expert in robotic surgery for these conditions. His institution is an 800 bed referral center recognised as one of the best hospitals for cancer treatment in India. It is equipped with state of art technological equipment including the Da Vinci Xi HD robotic system which is used by Dr. Gautam to advance the role of robotic surgery for the treatment of kidney cancer in India.

To know more about Dr. Gagan Gautam, please click here

To read a patient’s personal experience after kidney cancer surgery, please click here

If you would like to seek an appointment or would like to get in touch with him, please click here

To connect with him on social media, please visit facebook.com/roboticsurgerydelhi or follow him on twitter @DrGaganGautam

To visit his website, please go to http://www.roboticsurgerydelhi.com